Human and Rat Neocortical Development
The Development of the Human Neocortex
The link below is the pdf file of the entire book containing over 200 pages; the file is nearly 25 MB because of the extensive photographs included. The Laboratory of Developmental Neurobiology is offering this as a free book to anyone who wishes to learn more about human neocortical development. Enjoy reading! Please use the contact page to let us know what you think of our interpretations.
The Development of the Rat Neocortex
The photo series here shows the different levels we used to determine the time of origin of neurons in different parts of the neocortex with 3H-thymidine autoradiography (Chapter 3, Figure 3-6; pdf file #5, bottom list). L1-L5 are the levels from most anterior (1) to most posterior (5).
We think that the concepts presented in this book are relevant today, and this developmental treatise remains the most comprehensive study of neocortical development in any mammal. The recent research on gene expression studies confirms some of our observations and speculations about the mechanisms at work during neocortical development.
Rat Neocortical Development Book Files By Part and Chapter